… that the Hoxa-5 gene is differentially expressed among different lung cell types and that RA
participates in the regulation of Hoxa-5 gene expression in the developing mouse lung. We …

… cell-specific Hoxa-5 gene expression in fetal lung fibroblasts and MLE 12 cells in a dose-
and time-dependent manner. Maximal stimulation of Hoxa-5 expression … of Hoxa-5 in the …

… oping lung, we studied the temporal, spatial, and cellspecific … -5 paralog, Hoxa-5, may help
maintain expression of Hoxb5 in … lung and effects of gestational age and retinoic acid on their …

… for cis-acting regulatory sequences and associated trans-… activates retinoic acid receptors
that then interact with retinoic acid … by looking at the expression of cell specific markers by qRT-…

… N-myc and the retinoic acid receptors as transcriptional … analysis of fetal mouse and rat
lungs shows that Hoxa-5, Hoxb-5… animals, cell-specific genes and their regulatory regions. …

… regulatory region of lung-specific genes also demonstrated that normal promoter activity
required synergistic interaction of multiple cell-specific … -4 expression is induced by retinoic acid …

… expression has been shown to be regulated by RA in embryonic carcinoma cells and in
developing mouse lung … How HOXA5 expression is regulated by RA and the role of HOX gene in …

… All- trans retinoic acid and altered Hox transcription may be the cause of abnormalities in …
HC: Hoxa-5 in mouse developing lung: cell-specific expression and retinoic acid regulation. …

… regulated and cell-specific expression of Hoxb5, Nkx2.1, and … Interestingly, retinoic acid,
another important regulator of lung … Early postnatal lethality in Hoxa-5 mutant mice is attributable …

… and cell-specific expression of Hoxb5, Nkx2.1, and SP-C … genes in lung development mediates
epithelial cell-specific … , T 3 and retinoic acid regulation of distal airway development may …